Cartagena is a city that is located on the shores of the Caribbean Sea, in the northwestern part of the South American continent. If you are wondering where is Cartagena in Colombia, it is located in the north of the country and is the capital of the Bolívar region. Cartagena de Indias is known for their charm of colonial architecture, the excitement of a vivid night life, fascinating cultural festivals, and lush landscapes that will bring you the perfect vacation experience.